REVIEW: Saturday Night. The SNL story

#FormerNetworkExec #CallMeChato #snl
Review of Jason Reitman's Saturday Night movie.
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Cancers

Ivermectin, a potential anticancer drug derived from an antiparasitic drug

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/

Mechanisms of action

IVM induces different programmed cell death patterns in different tumor cells,

the main form of IVM induced programmed cell death is apoptosis.

Apoptosis

Programmed cell death

Autophagy

Lysosomal-dependent form of programmed cell death.

Pyroptosis

Inflammatory cell death induced by inflammasomes.

Kathleen T Ruddy, MD

https://twitter.com/bobanderson77/status/1797002359521866017/video/1

https://rumble.com/v4vk4pw-oncologist-kathleen-rudy-reveals-horse-dewormer-aka-ivermectin-cure-cancer.html

https://twitter.com/DocRuddy

https://rumble.com/v4vk4pw-oncologist-kathleen-rudy-reveals-horse-dewormer-aka-ivermectin-cure-cancer.html

Forms of cancer

Breast cancer

A malignant tumor produced by gene mutation in breast epithelial cells

Digestive system cancer

Gastric cancer is one of the most common malignant tumors worldwide.

Hepatocellular carcinoma is the fourth leading cause of cancer death worldwide.

Urinary system cancer

Renal cell carcinoma is a fatal malignant tumor of the urinary system derived from renal tubular epithelial cells.

Prostate cancer is a malignant tumor derived from prostate epithelial cells

Hematological cancer

Leukemia is a type of malignant clonal disease caused by abnormal hematopoietic stem cells

Reproductive system cancer

Cervical cancer is one of the most common gynecological malignancies

Ovarian cancer is a malignant cancer that lacks early clinical symptoms and has a poor therapeutic response.

Brain glioma

Glioma is the most common cerebral tumor

Glioblastoma, median survival time of 14-17 months

Respiratory system cancer

Nasopharyngeal carcinoma is a malignant tumor derived from epithelial cells of the nasopharyngeal mucosa.

Lung cancer has the highest morbidity and mortality among cancers

Melanoma

The most common malignant skin tumor with a high mortality rate.

Other papers

Ivermectin suppresses tumour growth and metastasis through degradation of PAK1 in oesophageal squamous cell carcinoma

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205794/

Antitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned cancer drug

https://pubmed.ncbi.nlm.nih.gov/32474842/

Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer

https://www.nature.com/articles/s41523-021-00229-5

Abstract 2320: Ivermectin suppresses pancreatic cancer via mitochondria dysfunction

https://aacrjournals.org/cancerres/article/82/12_Supplement/2320/701043/Abstract-2320-Ivermectin-suppresses-pancreatic

Video reviews

https://www.youtube.com/watch?v=vCgNaOvICsk

https://www.youtube.com/@dr.kathleenruddy1734/videos

https://www.youtube.com/watch?v=m_78xfHRHUY

https://www.youtube.com/watch?v=jaY2BeNnfy8

Hurricane Oscar Public Advisory

…OSCAR STEADY IN INTENSITY AS IT MOVES WEST-SOUTHWESTWARD… …LANDFALL EXPECTED IN CUBA LATER THIS AFTERNOON ALONG NORTH COASTLINE OF GUANTANAMO AND HOLGUIN PROVINCES…
As of 11:00 AM EDT Sun Oct 20
the center of Oscar was located near 20.7, -73.9
with movement WSW at 7 mph.
The minimum central pressure was 986 mb
with maximum sustained winds of about 80 mph.

Remnants of Nadine Public Advisory

…NADINE DISSIPATED OVER SOUTHERN MEXICO… …HEAVY RAINFALL AND FLASH FLOODING STILL EXPECTED OVER PARTS OF BELIZE, GUATEMALA, AND MEXICO…
As of 10:00 AM CDT Sun Oct 20
the center of Nadine was located near 16.5, -93.0
with movement WSW at 14 mph.
The minimum central pressure was 1007 mb
with maximum sustained winds of about 30 mph.

Remnants of Nadine Forecast Advisory

Issued at 1500 UTC SUN OCT 20 2024

Hurricane Oscar Public Advisory

…AIR FORCE RECONNAISSANCE FINDS OSCAR JUST SOUTHWEST OF THE COAST OF GREAT INAGUA ISLAND… …EXPECTED TO REACH GUANTANAMO OR HOLGUIN CUBA AS A HURRICANE LATER TODAY…
As of 8:00 AM EDT Sun Oct 20
the center of Oscar was located near 20.8, -73.6
with movement WSW at 12 mph.
The minimum central pressure was 986 mb
with maximum sustained winds of about 80 mph.

Italy Disrupts The LGBT Baby Trade By Passing A Ban On Overseas Surrogacy

Italy Disrupts The LGBT Baby Trade By Passing A Ban On Overseas Surrogacy

It’s a disturbing trend that has been spreading over the past few years:  Gay and Trans couples buying off surrogate mothers to have babies for them, then taking those babies and using them as fashion accessories for social media clout.  The trend includes bizarre newborn baby photo ops in which the couples (usually gay or trans men) pose in a hospital bed with the baby as if they just gave birth to it. 

While legal in many countries, the practice has some unsettling implications in terms of cultural respect for motherhood, the future life stability of children being used as props, and the normalization of gender identity mental illness.

The Italian government under Georgia Meloni, Italy’s first female prime minister, has closed the overseas loophole in the LGBT baby market.  It is one of the first governments to finally address and block the practice of IVF for surrogacy (in place since 2004), and they have now extended that ban to include the recruitment of surrogate mothers outside of the country.  In other words, it’s a complete ban on surrogate pregnancies.  Those who break the law face fines of up to $1 million and 2 years in prison.

Critics are calling the law a “monstrous attack” on the LGBT community and their ability to have a family.  Keep in mind, the law applies to all Italians, not just those that identify as gay or trans.  However, it is likely that the restrictions were specifically designed to stop the explosion of the LGBT baby trade and trans surrogacy.  Meloni has has described herself as a Christian mother and believes children should only be raised by a man and a woman.

Because the practice of surrogacy for gay male couples in particular has been limited until recently, there is scant data on the effects of the practice on children as they grow up.  There are multiple scientific studies that do show that children in gay households fare worse as they grow up than those in homes with a traditional mother and father. 

These problems include whether a child had grown up to need public assistance like welfare, were more likely to have anxiety or depression, were more likely to be abused, or were more apt engage in unhealthy habits such as having more sexual partners, smoking or using drugs.

Whenever such unbiased and non-political studies are released, they are immediately attacked by gay activist groups for “bigotry”.  Today, it is unlikely that these kinds of studies will ever be funded, let alone released to the public.  The science on the social effects of the gay and trans lifestyle is fully suppressed in the 2020s. 

Common arguments against the surrogacy ban include claims that surrogacy is necessary in order to counter Italy’s population decline.  But leftist organizations exploit the western population drop as a rationale for many of their agendas, including their mass immigration agenda. It’s not enough for a society to simply have more babies, they need stable homes for those babies where the children are not merely there to satisfy the narcissism of LGBT activists.  

Italy, it seems, has decided to err on the side of caution.

Tyler Durden
Sun, 10/20/2024 – 07:35

Leaked US Intelligence Documents Related To Israel’s Attack Preparations On Iran Appear Online

from ZeroHedge: A major leak of US classified documents has appeared online Saturday… or we should qualify alleged leaks of at least two TOP SECRET documents, with both marked NOFORN – which is among the highest classifications – given it indicates the specific intelligence cannot be shared with allied foreign intelligence agencies (with the exception of the “Five Eyes”). A breaking Axios report suggests their authenticity: […]

Hurricane Oscar Public Advisory

…OSCAR MAKES LANDFALL ON GREAT INAGUA ISLAND… …EXPECTED TO REACH GUANTANAMO OR HOLGUIN CUBA AS A HURRICANE THIS AFTERNOON…
As of 5:00 AM EDT Sun Oct 20
the center of Oscar was located near 21.1, -73.1
with movement W at 12 mph.
The minimum central pressure was 988 mb
with maximum sustained winds of about 80 mph.

Tropical Depression Nadine Forecast Discussion

Issued at 400 AM CDT Sun Oct 20 2024